PTC Therapeutics has leased 360,000 square feet for a new corporate headquarters in Warren, in a deal that marks one of New Jersey’s largest office leases of the past decade.

The drug maker, which is currently headquartered in South Plainfield, will occupy two full buildings at 400 and 500 Warren Corporate Center Drive. It’s leasing the space from a joint venture of Rubenstein Partners LP and Vision Real Estate Partners, which announced the blockbuster deal Thursday and have repositioned much of the five-building campus off Interstate 78.

Jeff Zell and Louis Kluger of JM Zell Partners represented PTC in the transaction, while Robert Donnelly Sr., Robert Donnelly Jr., Paul Giannone, Todd Elfand and Kevin Carton of Cushman & Wakefield represented ownership alongside Robert Klausner of Fox Rothschild LLP. The biopharma company will relocate after a build-out that will include offices, collaboration and conferencing spaces and research laboratories, with construction set to begin this month.

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